one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the treatment of multiple myeloma. Its synthesis or study is crucial for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-one): A essential compound within the synthesis of imatinib, a drug that targets specific varieties of most cancers, which includes chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the production approach and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the remedy of colorectal most cancers and smaller mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, which have numerous programs, like antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of CAS NO. 314771-76-1 vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four 3-(4-Nitro-1-oxo-1 to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved in the synthesis of various gluconic acid derivatives, which can be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication employed to handle sort two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).